Renoprotective effect of vildagliptin following hepatic ischemia/reperfusion injury

Renoprotective effect of crocin following liver ischemia/ reperfusion injury in Wistar rats

Objective(s): The objectives of the current study were to evaluate the effects of hepatic ‎ischemia/reperfusion (IR) injury on the activity of antioxidant enzymes, biochemical factors, and ‎histopathological changes in rat kidney, and to investigate the effect of crocin on IR-‎related changes. Materials and Methods: Thirty-two male Wistar rats were randomly allocated into four groups (n=8). The...

Renoprotective effect of crocin following liver ischemia/ reperfusion injury in Wistar rats

Objectives The objectives of the current study were to evaluate the effects of hepatic ischemia/reperfusion (IR) injury on the activity of antioxidant enzymes, biochemical factors, and histopathological changes in rat kidney, and to investigate the effect of crocin on IR-related changes. Materials and Methods Thirty-two male Wistar rats were randomly allocated into four groups (n=8). They wer...

Renoprotective effect of metformin.

Orexin-A Improves Hepatic Injury Following Renal Ischemia Reperfusion in Rats

Introduction: Orexins are novel neuropeptides that are localized in neurons in the lateral hypothalamus. They are implicated in a wide variety of physiological functions. Orexin peptides and receptors are found in many peripheral organs such as kidneys. It has been demonstrated that exogenous orexin-A can induce protective effects against ischemia–reperfusion injury in many organs. The goal ...

Effect of hepatic injury on adjuvant arthritis.

Hench (1933) described the ameliorating effect of hepatic disease on rheumatoid arthritis. Although jaundice was thought to be the determining factor in these remissions, it was not possible to reproduce the phenomenon by administration of bilirubin and bile salts (Hench, 1940), and a satisfactory explanation of its mechanism has never been offered (Hill and Holley, 1966). This was investigated...